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Destiny trial hemicraniectomy

WebThere are multiple international randomized controlled trials evaluating the outcomes of DC in the setting of space-occupying malignant infarction. Three European randomized control trials, the Dutch HAMLET trial, the German DESTINY trial, and the French DECIMAL trial, compared hemicraniectomy to standard medical treatment [4, 15, 26, 38]. All ... WebConclusions. At 6 months, decompressive craniectomy in patients with traumatic brain injury and refractory intracranial hypertension resulted in lower mortality and higher rates of vegetative ...

Decompressive Surgery for the Treatment of …

WebGeneral eligibility criteria for three major trials (DECIMAL, DESTINY, HAMLET) evaluating decompressive hemicraniectomy for malignant middle cerebral artery territory infarction. Inclusion criteria: Age 18 to 60 years* Clinical deficits suggestive of infarction in the territory of the MCA with a NIHSS score ≥16 ; iperf tcp丢包率 https://thepreserveshop.com

Hemicraniectomy in older patients with extensive middle …

WebBackground and Purpose— Decompressive surgery (hemicraniectomy) for life-threatening massive cerebral infarction represents a controversial issue in neurocritical care … http://www.neuroicudoc.com/2014/03/hemicraniectomy-in-older-stroke.html#!#:~:text=DESTINY%20II%20was%20a%20multicenter%20randomized%20controlled%20trial,randomized%20across%20the%2013%20participating%20sites%20in%20Germany. WebThe mean percentage of men enrolled in the trials reviewed was ≥50%, ranging from 50% (DESTINY 2) to 72% (Zhao et al., 2012), except in the DESTINY and DECIMAL trials, where men represented 47% of participants. Sex was not explored as a potential effect modifier in any of the hemicraniectomy trials. iperf switches

Hemicraniectomy – An Overview of Current Status and Future ...

Category:Hemicraniectomy in older stroke patients: the DESTINY II trial

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Destiny trial hemicraniectomy

Decompressive Hemicraniectomy in Elderly Patients With Space …

WebAug 9, 2024 · In this single-center cohort of elderly patients with space-occupying MCA infarction and decompressive hemicraniectomy, the probability for survival without severe disability was low. ... A pooled analysis of individual patient data from the single-center cohort and a DESTINY 2 trial subgroup was performed to identify factors associated with ... Web陈会生,周中和沈阳军区总医院神经内科,辽宁沈阳 110016恶性大脑中动脉脑梗死通常指继发于颈内动脉或大脑中动脉m1段闭塞 ...

Destiny trial hemicraniectomy

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WebJan 14, 2016 · All three controlled trials had an age limit of 60 years for inclusion. More recently the DESTINY II trial investigated how hemicraniectomy affects patients older than 60 years of age. ... A recent trial, DESTINY II, focusing on this elderly population of stroke-afflicted patients, found better outcomes: mRS of 0–4 present in 38% in the ... WebFor the outcome ‘functional outcome score 0-3 mRS at 1 year’, the HAMLET trial has a much smaller effect size than in the DESTINY and DECIMAL trials, which show a trend towards benefit of decompressive hemicraniectomy. Quality of life reported by the HAMLET trial might therefore be expected to be lower than in the other trials.

WebApr 18, 2012 · Decompressive hemicraniectomy (DHC) has proven efficacious for the treatment of malignant middle cerebral artery infarction (mMCAI) only in patients less than 60 years. This study aimed to assess the effectiveness of DHC in patients up to 80. ... DECIMAL and DESTINY trials) [6, 7]. Thus, a dichotomized functional outcome analysis … WebOct 2, 2012 · Randomized controlled trials (RCT) on the treatment of severe space-occupying infarction of the middle cerebral artery (malignant MCA infarction) showed that early decompressive hemicraniectomy (DHC) is life saving and improves outcome without promoting most severe disablity in patients aged 18–60 years. It is, however, unknown …

WebDec 19, 2024 · The initial three randomised controlled trials (DECIMAL , HAMLET and DESTINY ) considered individually or with pooled patient data analysis demonstrated that hemicraniectomy was superior to medical management alone in both survival and functional outcome measured using the modified Rankin score (mRS) where good … WebIn this prospective, randomized, controlled, open, multicenter trial, we randomly assigned patients, in a 1:1 ratio, to treatment in the ICU alone …

WebOct 22, 2024 · Early decompressive hemicraniectomy had a proven role in reduction of mortality and improving functional outcome in cases with malignant MCA infarction. Among other factors, timing of surgery and the preoperative clinical condition were factors that affected the final outcome. ... the German DESTINY trial, the Dutch HAMLET trial, and …

WebFeb 9, 2007 · 93 patients were included in the pooled analysis. More patients in the decompressive-surgery group than in the control group had an mRS≤4 (75% vs 24%; pooled absolute risk reduction 51% [95% CI 34–69]), an mRS≤3 (43% vs 21%; 23% [5–41]), and survived (78% vs 29%; 50% [33–67]), indicating numbers needed to treat of two for … iperf tcp 速度が出ないWebForschungsgemeinschaft; DESTINY II Current Controlled Trials number, ISRCTN21702227.) ... by sufficient evidence from clinical trials. 9,10 Decompressive hemicraniectomy (temporary iperf techplayonWebOct 2, 2012 · Background: Randomized controlled trials (RCT) on the treatment of severe space-occupying infarction of the middle cerebral artery (malignant MCA infarction) showed that early decompressive hemicraniectomy (DHC) is life saving and improves outcome without promoting most severe disablity in patients aged 18-60 years. It is, however, … iperf testing tutorialWebDESTINY II: Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke. DESTINY II Investigators. NEJM 2014;370:1091-1100. … iperf threadsWebMar 24, 2014 · This occurred in 38% of the hemicraniectomy group compared with 18% of the control group (odds ratio, 2.91; 95% confidence interval, 1.06 - 7.49; P = .04). Mortality was reduced by 43% in the ... iperf timed outWebHofmeijer and colleagues presented the results of the HAMLET study (Hemicraniectomy After Middle cerebral artery infarction with Life-threatening Edema Trial), one of three … iperf test microsoftWebMar 21, 2014 · DESTINY II was a multicenter randomized controlled trial (RCT) of decompressive hemicraniectomy surgery vs. medical care for patients age >60 with large hemispheric ischemic strokes with brain … iperf throughput calculation